Cizzle Biotechnology Holdings plc (LON:CIZ), the UK based diagnostics developer, has announced the publication of the Company’s Annual Report and Financial Statements for the year ended 31 December 2023:
Cizzle Biotechnoloy is developing a blood test for the early detection of lung cancer. The Company is a spin- out from the University of York, founded in 2006, around the work of Professor Coverley and colleagues. Its proof-of-concept prototype test is based on the ability to detect a stable plasma biomarker, a variant of CIZ1 known as CIZ1B. CIZ1 is a naturally occurring cell nuclear protein involved in DNA replication, and the targeted CIZ1B variant is highly correlated with early-stage lung cancer.